Best Acne Spot Treatments

Bath & Body Fragrance Hair Care Makeup Skincare Tools & Accessories
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46 main image.
EltaMD
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46
$47
BestSeller
3,105
Black Cumin and Cajeput Serum Concentrate main image.
Odacité
Black Cumin and Cajeput Serum Concentrate
$36
17
Deep Acne Liquid Patch main image.
Dermalogica
Deep Acne Liquid Patch
$35
1
Cleanance Concentrate Blemish Control Serum main image.
Avène
Cleanance Concentrate Blemish Control Serum
$40
3,853
Breakout Box Acne Treatment Kit main image.
Patchology
Breakout Box Acne Treatment Kit
$20
BestSeller
501
Silymarin CF main image.
SkinCeuticals
Silymarin CF
$185
BestSeller
267
Targeted Blemish Treatment main image.
Ogee
Targeted Blemish Treatment
$38
169
Blackhead Solutions Self-Heating Blackhead Extractor main image.
Clinique
Blackhead Solutions Self-Heating Blackhead Extractor
$36
124
PowerSpot Blemish Lotion main image.
M-61
PowerSpot Blemish Lotion
$16
BestSeller Exclusive
51
Clarifying Serum main image.
Dr. Barbara Sturm
Clarifying Serum
$260
31
Clearly Corrective Dark Spot Solution main image.
Kiehl's Since 1851
Clearly Corrective Dark Spot Solution
$65
1,710
Retinol 0.5 main image.
SkinCeuticals
Retinol 0.5
$90
BestSeller
273
Acne Solutions Acne + Line Correcting Serum main image.
Clinique
Acne Solutions Acne + Line Correcting Serum
$57
212
Retinol 0.3 main image.
SkinCeuticals
Retinol 0.3
$80
BestSeller
159
Epidermal Repair main image.
SkinCeuticals
Epidermal Repair
$90
BestSeller
111
Perfect Peel main image.
M-61
Perfect Peel
$72
BestSeller Exclusive
107
Active Serum main image.
IS Clinical
Active Serum
$148
35
Vitablast C Dark Spot Corrector Stick main image.
M-61
Vitablast C Dark Spot Corrector Stick
$92
Exclusive
31
Phyto-Blanc Targeted Dark Spot Corrector main image.
Sisley Paris
Phyto-Blanc Targeted Dark Spot Corrector
$215
8
Absolute Purtiy Toner main image.
Tracie Martyn
Absolute Purtiy Toner
$65
2

When a pesky blemish tries to steal the spotlight, the best acne spot treatments are your secret weapon for a clearer, more confident complexion. Think of these targeted solutions as your personal beauty troubleshooters—ready to step in and help you face the day with poise. Whether you’re prepping for a big event or simply want to keep your skin looking its best, our curated selection empowers you to tackle breakouts head-on, so you can get back to glowing.

Best Sellers

Dramatically Different Moisturizing Lotion 1.7 oz main image.
Clinique
Dramatically Different Moisturizing Lotion 1.7 oz
$17
10,046
Crème de La Mer Face Cream 2 oz main image.
La Mer
Crème de La Mer Face Cream 2 oz
$390
8,343
Ultra Facial Cream 1.7 oz main image.
Kiehl's Since 1851
Ultra Facial Cream 1.7 oz
$39
8,094
Liquid Facial Soap OILY main image.
Clinique
Liquid Facial Soap OILY
$28
7,716