Best Acne Spot Treatments

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PowerSpot Blemish Lotion main image.
M-61
PowerSpot Blemish Lotion
$16
Exclusive
51
Black Cumin and Cajeput Serum Concentrate main image.
Odacité
Black Cumin and Cajeput Serum Concentrate
$36
17
Deep Acne Liquid Patch main image.
Dermalogica
Deep Acne Liquid Patch
$35
1
Blemish Balm with Plant Based Salicylic Acid main image.
OSEA
Blemish Balm with Plant Based Salicylic Acid
$54
BestSeller
543
Cleanance Concentrate Blemish Control Serum main image.
Avène
Cleanance Concentrate Blemish Control Serum
$40
3,852
Breakout Box Acne Treatment Kit main image.
Patchology
Breakout Box Acne Treatment Kit
$20
BestSeller
501
Blackhead Solutions Self-Heating Blackhead Extractor main image.
Clinique
Blackhead Solutions Self-Heating Blackhead Extractor
$36
124
Acne Gel With OmniSome main image.
PCA Skin
Acne Gel With OmniSome
$72
101
Clarifying Serum main image.
Dr. Barbara Sturm
Clarifying Serum
$260
31
LightStim for Acne main image.
LightStim
LightStim for Acne
$169
7
Age Intervention Duality main image.
Jan Marini
Age Intervention Duality
$115
2
Clearly Corrective Dark Spot Solution main image.
Kiehl's Since 1851
Clearly Corrective Dark Spot Solution
$65
1,690
Acne Solutions Clarifying Lotion main image.
Clinique
Acne Solutions Clarifying Lotion
$22
916
Retexturing Activator main image.
SkinCeuticals
Retexturing Activator
$94
BestSeller
317
Retinol 0.5 main image.
SkinCeuticals
Retinol 0.5
$90
BestSeller
270
Retinol 0.3 main image.
SkinCeuticals
Retinol 0.3
$80
BestSeller
154
Perfect Peel main image.
M-61
Perfect Peel
$72
BestSeller Exclusive
106
Blemish Control Bar main image.
PCA Skin
Blemish Control Bar
$62
53
Active Serum main image.
IS Clinical
Active Serum
$148
BestSeller
35
Vitablast C Dark Spot Corrector Stick main image.
M-61
Vitablast C Dark Spot Corrector Stick
$92
Exclusive
31
Deeply Purifying Mask With Tropical Resins main image.
Sisley Paris
Deeply Purifying Mask With Tropical Resins
$160
14
Absolute Purtiy Toner main image.
Tracie Martyn
Absolute Purtiy Toner
$65
2
Clenziderm M.D. Pore Therapy main image.
Obagi
Clenziderm M.D. Pore Therapy
$49
1

When a pesky blemish tries to steal the spotlight, the best acne spot treatments are your secret weapon for a clearer, more confident complexion. Think of these targeted solutions as your personal beauty troubleshooters—ready to step in and help you face the day with poise. Whether you’re prepping for a big event or simply want to keep your skin looking its best, our curated selection empowers you to tackle breakouts head-on, so you can get back to glowing.

Best Sellers

Dramatically Different Moisturizing Lotion 4.2 oz main image.
Clinique
Dramatically Different Moisturizing Lotion 4.2 oz
$34
9,906
Crème de La Mer Face Cream 2 oz main image.
La Mer
Crème de La Mer Face Cream 2 oz
$390
8,190
Ultra Facial Cream 4.2 oz main image.
Kiehl's Since 1851
Ultra Facial Cream 4.2 oz
$72
8,058
Liquid Facial Soap MILD main image.
Clinique
Liquid Facial Soap MILD
$28
7,652