Best Acne Spot Treatments

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Black Cumin and Cajeput Serum Concentrate main image.
Odacité
Black Cumin and Cajeput Serum Concentrate
$36
17
Truly Targeted Acne-Clearing Solution main image.
Kiehl's Since 1851
Truly Targeted Acne-Clearing Solution
$30
4,456
Blemish Balm with Plant Based Salicylic Acid main image.
OSEA
Blemish Balm with Plant Based Salicylic Acid
$54
BestSeller
Silymarin CF main image.
SkinCeuticals
Silymarin CF
$185
BestSeller
259
Targeted Blemish Treatment main image.
Ogee
Targeted Blemish Treatment
$38
164
Blackhead Solutions Self-Heating Blackhead Extractor main image.
Clinique
Blackhead Solutions Self-Heating Blackhead Extractor
$36
123
Acne Gel With OmniSome main image.
PCA Skin
Acne Gel With OmniSome
$70
101
PowerSpot Blemish Lotion main image.
M-61
PowerSpot Blemish Lotion
$16
Exclusive
51
3 Phase Anti-Blemish Booster Serum main image.
111SKIN
3 Phase Anti-Blemish Booster Serum
$67.5
50
Clarifying Serum main image.
Dr. Barbara Sturm
Clarifying Serum
$260
31
LightStim for Acne main image.
LightStim
LightStim for Acne
$169
7
Age Intervention Duality main image.
Jan Marini
Age Intervention Duality
$115
2
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46 main image.
EltaMD
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46
$46
BestSeller
2,744
Clearly Corrective Dark Spot Solution main image.
Kiehl's Since 1851
Clearly Corrective Dark Spot Solution
$65
1,674
Acne Solutions Clarifying Lotion main image.
Clinique
Acne Solutions Clarifying Lotion
$22
916
TheraFace Mask main image.
Therabody
TheraFace Mask
$649.99
170
Epidermal Repair main image.
SkinCeuticals
Epidermal Repair
$90
106
Perfect Peel main image.
M-61
Perfect Peel
$72
BestSeller Exclusive
106
Active Serum main image.
IS Clinical
Active Serum
$148
BestSeller
35
Vitablast C Dark Spot Corrector Stick main image.
M-61
Vitablast C Dark Spot Corrector Stick
$92
BestSeller Exclusive
31
Phyto-Blanc Targeted Dark Spot Corrector main image.
Sisley-Paris
Phyto-Blanc Targeted Dark Spot Corrector
$215
8
Absolute Purtiy Toner main image.
Tracie Martyn
Absolute Purtiy Toner
$65
2
Clenziderm M.D. Pore Therapy main image.
Obagi
Clenziderm M.D. Pore Therapy
$49
1

When a pesky blemish tries to steal the spotlight, the best acne spot treatments are your secret weapon for a clearer, more confident complexion. Think of these targeted solutions as your personal beauty troubleshooters—ready to step in and help you face the day with poise. Whether you’re prepping for a big event or simply want to keep your skin looking its best, our curated selection empowers you to tackle breakouts head-on, so you can get back to glowing.

Best Sellers

Dramatically Different Moisturizing Lotion 4.2 oz main image.
Clinique
Dramatically Different Moisturizing Lotion 4.2 oz
$34
9,862
Crème de La Mer Face Cream 2 oz main image.
La Mer
Crème de La Mer Face Cream 2 oz
$390
8,183
Ultra Facial Cream 4.2 oz main image.
Kiehl's Since 1851
Ultra Facial Cream 4.2 oz
$72
8,024
Liquid Facial Soap MILD main image.
Clinique
Liquid Facial Soap MILD
$14
7,612