Best Acne Spot Treatments

Bath & Body Fragrance Hair Care Makeup Skincare Tools & Accessories
Black Cumin and Cajeput Serum Concentrate main image.
Odacité
Black Cumin and Cajeput Serum Concentrate
$25.2
17
Truly Targeted Acne-Clearing Solution main image.
Kiehl's Since 1851
Truly Targeted Acne-Clearing Solution
$30
4,477
Deep Acne Liquid Patch main image.
Dermalogica
Deep Acne Liquid Patch
$36
1
Blemish + Age Defense main image.
SkinCeuticals
Blemish + Age Defense
$115
BestSeller
728
Targeted Blemish Treatment main image.
Ogee
Targeted Blemish Treatment
$39
192
PowerSpot Pad main image.
M-61
PowerSpot Pad
$70
BestSeller Exclusive
69
PowerSpot Blemish Lotion main image.
M-61
PowerSpot Blemish Lotion
$20
BestSeller Exclusive
54
Clarifying Serum main image.
Dr. Barbara Sturm
Clarifying Serum
$260
33
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46 main image.
EltaMD
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46
$47
BestSeller
3,251
Expertly Clear Acne-Treating & Preventing Lotion main image.
Kiehl's Since 1851
Expertly Clear Acne-Treating & Preventing Lotion
$39
1,948
Clearly Corrective Dark Spot Solution main image.
Kiehl's Since 1851
Clearly Corrective Dark Spot Solution
$65
1,811
Retexturing Activator main image.
SkinCeuticals
Retexturing Activator
$100
340
Acne Solutions Acne + Line Correcting Serum main image.
Clinique
Acne Solutions Acne + Line Correcting Serum
$59
216
TheraFace Mask main image.
Therabody
TheraFace Mask
$649.99
183
Perfect Peel main image.
M-61
Perfect Peel
$72
BestSeller Exclusive
111
Active Serum main image.
IS Clinical
Active Serum
$155
BestSeller
36
Vitablast C Dark Spot Corrector Stick main image.
M-61
Vitablast C Dark Spot Corrector Stick
$92
BestSeller Exclusive
32
Deeply Purifying Mask With Tropical Resins main image.
Sisley Paris
Deeply Purifying Mask With Tropical Resins
$165
14
Phyto-Blanc Targeted Dark Spot Corrector main image.
Sisley Paris
Phyto-Blanc Targeted Dark Spot Corrector
$225
9
Absolute Purtiy Toner main image.
Tracie Martyn
Absolute Purtiy Toner
$65
2
Acne Biotic Moisturizer main image.
Dermalogica
Acne Biotic Moisturizer
$77
1

When a pesky blemish tries to steal the spotlight, the best acne spot treatments are your secret weapon for a clearer, more confident complexion. Think of these targeted solutions as your personal beauty troubleshooters—ready to step in and help you face the day with poise. Whether you’re prepping for a big event or simply want to keep your skin looking its best, our curated selection empowers you to tackle breakouts head-on, so you can get back to glowing.

Best Sellers

Dramatically Different Moisturizing Lotion 4.2 oz main image.
Clinique
Dramatically Different Moisturizing Lotion 4.2 oz
$34
10,345
Dramatically Different Moisturizing Lotion+ main image.
Clinique
Dramatically Different Moisturizing Lotion+
$49
9,917
Ultra Facial Cream 4.2 oz main image.
Kiehl's Since 1851
Ultra Facial Cream 4.2 oz
$72
8,728
Crème de La Mer Face Cream 0.5 oz main image.
La Mer
Crème de La Mer Face Cream 0.5 oz
$100
8,394