SkinCeuticals

The P-TIOX Peptide Power Duo

    Achieve your most radiant, glass-like complexion with the SkinCeuticals P-TIOX Serum and P-TIOX Cream. 

    The P-TIOX Peptide Power DuoThe P-TIOX Peptide Power DuoThe P-TIOX Peptide Power DuoThe P-TIOX Peptide Power DuoThe P-TIOX Peptide Power DuoThe P-TIOX Peptide Power Duo

    Achieve your most radiant, glass-like complexion with the SkinCeuticals P-TIOX Serum and P-TIOX Cream. 

    SkinCeuticals P-TIOX main image
    P-TIOX
    P-TIOX Cream variant: Default Title main image
    P-TIOX Wrinkle-Modulating Peptide Cream

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    The P-TIOX Peptide Power Duo

    $264

    Why We Love It

    Reduces the appearance of 9 types of expression lines, even those hard to treat with neurotoxin injections

    Intensely moisturizes skin up to 24 hours after application

    Visibly reduces deep-set wrinkles and pores

    "P-TIOX is ideal for anyone looking to visibly smooth expression lines and achieve that glass skin look. This advanced peptide serum is inspired by the effects of neurotoxin injections and is clinically proved to improve the appearance of 9 types of wrinkles. I love how lightweight and layerable it is too, it fits easily into any skincare routine."

    Cori Ramos, SkinCeuticals Pro & Licensed Aesthetician

    As we age, expression lines and visible pores become more pronounced. P-TIOX Cream helps visibly smooth lines, refine pores, and improve skin texture over time. I recommend it both as a daily topical solution and to complement in-office injections for both men and women.

    Cori Ramos, SkinCeuticals Pro & Licensed Aesthetician

    Product Information

    Product Information

    Description

    This potent duo begins with P-TIOX Serum, a peptide-powered formula clinically proven to reduce the appearance of 9 types of expression lines and reveal glass skin radiance. Inspired by neurotoxin injections, its patent-pending blend of advanced peptides amplified by PHA, Niacinamide, and Laminaria Extract visibly refines texture and evens skin tone. Complete the regimen with P-TIOX Cream, powered by 10% Myrixin™ and 2% tripeptide technology to visibly smooth deep-set lines, reduce pore visibility, and deliver deep hydration without greasiness. Together, this synergistic combination delivers glass skin radiance in just 1 week, tested to complement professional neurotoxin injection results.

    UPC:

    Key Benefits

    • P-TIOX: Reduces the appearance of 9 types of expression lines, even those neurotoxin injections do not treat. Reveals glass skin radiance in 1 week of use. Hydrates skin up to 24 hours after application. Improves skin barrier with 1 application.
    • P-TIOX Cream: Visibly reduces deep-set wrinkles and pores. Smooths skin texture with patent-pending Myrixin™ and advanced peptides. Achieves glass skin appearance when paired with P-TIOX serum. Boosts hydration by +94% in just 1 hour.
    • Suitable for all skin types and tones.
    • Physician-tested to complement neurotoxin injections.
    Q&A

    Q&A

    What are the key differences between P-TIOX Serum and P-TIOX Cream?
    P-TIOX Serum is a concentrated treatment that targets visible expression lines and supports skin smoothness resulting in glass skin radiance with a fluid, transparent formula. P-TIOX Cream complements the serum by addressing pores, deep-set wrinkles, and surface texture while delivering hydration in a fresh cream texture that leaves a non-greasy finish. Used together, they create a complete routine for achieving a glass skin effect.
    Is it better to use anti-wrinkle serums at night or day?
    P-TIOX anti-wrinkle serum should be used twice daily. Apply the peptide serum to a dry face morning and night.
    What age should you start using P-TIOX anti-wrinkle serum?
    Formulas like P-TIOX can be used starting in your 20s. By incorporating an anti-wrinkle peptide serum into your skincare routine early, you can reduce the formation of wrinkles over time and improve the visible appearance of existing contraction lines and wrinkles.
    Do neuro-peptide serums reduce face wrinkles?
    Yes, peptide serums like P-TIOX anti-wrinkle serum visibly reduce face wrinkles. This anti-wrinkle serum is formulated with an advanced peptide complex that combines hexapeptide and dipeptide to reduce the formation and visible appearance of contraction lines and wrinkles. This formula is combined with polyhydroxy acid, niacinamide, and laminaria extract to encourage cell turnover and improve skin texture.
    How does an anti-wrinkle serum work?
    Anti-wrinkle serums work in several ways. P-TIOX contains an advanced peptide complex that is inspired by neurotoxin injection technology to reduce the appearance of wrinkles. This peptide complex works to help reduce the formation and visible appearance of contraction lines and wrinkles.
    How does P-TIOX Cream work?
    P-TIOX Cream uses a patented combination of proprietary Myrixin™ and tripeptide technologies to visibly reduce deep-set wrinkles, refine texture, and help minimize the appearance of enlarged pores. Myrixin™ helps modulate oil activity, while the tripeptide supports structural firmness and surface smoothness. This protective gel cream contains water-bursting micro-droplets that melt into the skin for rapid absorption, delivering instant smoothing and visible texture correction.
    How long does it take for P-TIOX Cream to work?
    Visible improvements, such as reduced pore visibility, can be seen in as little as one month. Continued daily use helps improve the appearance of deep-set wrinkles and refine overall texture. For optimal results, P-TIOX Cream should be used consistently and paired with P-TIOX serum to support the full glass skin routine.
    Can you use P-TIOX Cream under the eyes?
    Yes, you can apply P-TIOX Cream around the eyes. Follow the instructions to apply the cream twice daily to face, neck, and around the eyes. Clinical testing for P-TIOX Cream showed -28% under eye line correction.
    Is P-TIOX Cream suitable for men's skin?
    Yes. P-TIOX Cream is well-suited for men's skin, which often exhibits higher oil production, and more visible pores. This anti-wrinkle cream's patented Myrixin™ and tripeptide technologies help refine texture, reduce pore appearance, and oil production, all common concerns in men's skincare. The lightweight, non-greasy formula melts into the skin, absorbing quickly and supporting smoother, clearer skin without heaviness. This makes it an effective daily moisturizer for men seeking visible improvement in skin clarity and surface refinement.
    Clinical Trials

    Clinical Trials

    Before + After
    • +94%
      increase in hydration in 1 hour*
    • 50%
      reduction in sebum accumulation after 8 hours*
    • -33%
      reduction in wrinkles in 12 weeks**
    • -30%
      reduction in pore visibility in 12 weeks**
    • +20%
      improvement in skin quality in 12 weeks**
    • 20%
      reduction in global fine lines***
    • 16%
      improvement in smoothness***
    • 10%
      improvement in radiance***

    *(P-TIOX Cream) Instrumental test, 31 women, 22-45 y.o.

    **(P-TIOX Cream) Clinical testing of 77 subjects after 12 weeks

    ***(P-TIOX) A 12-week, single center clinical study was conducted on 82 females with Fitzpatrick type I-VI, (52% of subjects with sensitive skin), ages 34-65 and mild to moderate wrinkles, fine lines, pore appearance, rough skin texture evaluated by dermatologist. Efficacy evaluations were conducted at baseline, week 1, week 2, week 4, week 8 and week 12.

    Ingredients

    Ingredients

    Advanced Peptide Complex - 2% Hexapeptide + 2% Dipeptide (P-TIOX)

    Known to help reduce the appearance of contraction lines.

    5% PHA (P-TIOX)

    A gentle chemical exfoliant to help improve skin texture and enhance skin radiance.

    5% Niacinamide (P-TIOX)

    Strengthens the skin's moisture barrier and reduces the appearance of discoloration.

    1% Laminaria Extract (P-TIOX)

    Known to hydrate, soothe skin, and improve wrinkle correction.

    10% Myrixin™ (P-TIOX Cream)

    A flavonoid-rich complex inspired by neurotoxin-like effects which targets deep-set wrinkles.

    2% Tripeptide (P-TIOX Cream)

    Designed to help improve the appearance of key contraction lines.

    1% Crystalide Micropeptide (P-TIOX Cream)

    Helps promote skin transparency and radiance.

    5% Niacinamide + LHA + Zinc PCA (P-TIOX Cream)

    Visibly refines skin texture, reduces pores, and balances oil for visibly smoother skin.

    See Full Ingredients List See Full Ingredients List

    P-TIOX: Aqua / Water / Eau / Niacinamide / Gluconolactone / Butylene Glycol / Peg/Ppg/Polybutylene Glycol-8/5/3 Glycerin / Alcohol Denat. / Pentylene Glycol / Methyl Gluceth-20 / Glycerin / Potassium Hydroxide / Hydroxyethylcellulose / Salicylic Acid / Chlorphenesin / Phytic Acid / Adenosine / Sodium Benzoate / Laminaria Digitata Extract / Dipeptide Diaminobutyroyl Benzylamide Diacetate / Acetyl Hexapeptide-8

    P-TIOX Wrinkle-Modulating Peptide Cream: aqua / water / eau, butylene glycol, niacinamide, glycerin, dicaprylyl carbonate, pentylene glycol, cetearyl alcohol, 1,2-hexanediol, isododecane, c14-22 alcohols, caprylic/capric triglyceride, vinyl dimethicone, macadamia integrifolia seed oil, glyceryl stearate se, c12-20 alkyl glucoside, nymphaea alba flower extract, acrylates/c10-30 alkyl acrylate crosspolymer, butyrospermum parkii butter / shea butter, c12-16 alcohols, tromethamine, psidium guajava fruit extract, camellia sinensis leaf extract, allium sativum bulb extract / garlic bulb extract, zinc pca, capryloyl salicylic acid, psidium guajava leaf extract, luffa cylindrica fruit extract, hydrogenated lecithin, palmitic acid, cetyl palmitate, ethylhexylglycerin, adenosine, sorbitan stearate, polysorbate 80, tocopherol, ceramide np, dipeptide diaminobutyroyl benzylamide diacetate, sodium benzoate, citric acid, palmitoyl tetrapeptide-10

    How To Use

    How To Use

    • Twice daily, apply 4 to 6 drops of P-TIOX serum to the palm of the hand and dab onto the forehead, cheeks, and chin.
    • Next, dispense a small amount of P-TIOX Cream into clean hands.
    • Gently press cream evenly into skin on face, neck and around the eyes In the morning.
    • Complete your regimen with a SkinCeuticals broad-spectrum sunscreen.
    Shipping & Returns

    Shipping & Returns

    Bluemercury.com purchases can be returned free of charge to your local store or by mail within 90 days of purchase. Exchanges may only be completed in-store.

    BlueRewards members receive free standard shipping on all orders.

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