Best Acne Spot Treatments

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Black Cumin and Cajeput Serum Concentrate main image.
Odacité
Black Cumin and Cajeput Serum Concentrate
$36
17
Truly Targeted Acne-Clearing Solution main image.
Kiehl's Since 1851
Truly Targeted Acne-Clearing Solution
$30
4,458
Deep Acne Liquid Patch main image.
Dermalogica
Deep Acne Liquid Patch
$35
1
Blemish Balm with Plant Based Salicylic Acid main image.
OSEA
Blemish Balm with Plant Based Salicylic Acid
$54
BestSeller
Cleanance Concentrate Blemish Control Serum main image.
Avène
Cleanance Concentrate Blemish Control Serum
$40
3,852
Silymarin CF main image.
SkinCeuticals
Silymarin CF
$185
BestSeller
263
Targeted Blemish Treatment main image.
Ogee
Targeted Blemish Treatment
$38
168
Blackhead Solutions Self-Heating Blackhead Extractor main image.
Clinique
Blackhead Solutions Self-Heating Blackhead Extractor
$36
124
Acne Gel With OmniSome main image.
PCA Skin
Acne Gel With OmniSome
$72
101
Clarifying Serum main image.
Dr. Barbara Sturm
Clarifying Serum
$260
31
LightStim for Acne main image.
LightStim
LightStim for Acne
$169
7
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46 main image.
EltaMD
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46
$47
BestSeller
3,097
Clearly Corrective Dark Spot Solution main image.
Kiehl's Since 1851
Clearly Corrective Dark Spot Solution
$65
1,690
Acne Solutions Clarifying Lotion main image.
Clinique
Acne Solutions Clarifying Lotion
$22
919
Clearing Skin Wash main image.
Dermalogica
Clearing Skin Wash
$72
517
Retexturing Activator main image.
SkinCeuticals
Retexturing Activator
$94
319
TheraFace Mask main image.
Therabody
TheraFace Mask
$649.99
173
Retinol 0.3 main image.
SkinCeuticals
Retinol 0.3
$80
BestSeller
155
Blemish Control Bar main image.
PCA Skin
Blemish Control Bar
$62
53
Active Serum main image.
IS Clinical
Active Serum
$92
BestSeller
35
Vitablast C Dark Spot Corrector Stick main image.
M-61
Vitablast C Dark Spot Corrector Stick
$92
Exclusive
31
Deeply Purifying Mask With Tropical Resins main image.
Sisley Paris
Deeply Purifying Mask With Tropical Resins
$160
14
Phyto-Blanc Targeted Dark Spot Corrector main image.
Sisley Paris
Phyto-Blanc Targeted Dark Spot Corrector
$215
8
Absolute Purtiy Toner main image.
Tracie Martyn
Absolute Purtiy Toner
$65
2

When a pesky blemish tries to steal the spotlight, the best acne spot treatments are your secret weapon for a clearer, more confident complexion. Think of these targeted solutions as your personal beauty troubleshooters—ready to step in and help you face the day with poise. Whether you’re prepping for a big event or simply want to keep your skin looking its best, our curated selection empowers you to tackle breakouts head-on, so you can get back to glowing.

Best Sellers

Dramatically Different Moisturizing Lotion 4.2 oz main image.
Clinique
Dramatically Different Moisturizing Lotion 4.2 oz
$34
9,923
Crème de La Mer Face Cream 2 oz main image.
La Mer
Crème de La Mer Face Cream 2 oz
$390
8,191
Ultra Facial Cream 1.7 oz main image.
Kiehl's Since 1851
Ultra Facial Cream 1.7 oz
$39
8,067
Liquid Facial Soap OILY main image.
Clinique
Liquid Facial Soap OILY
$28
7,652