Best Acne Spot Treatments

Bath & Body Fragrance Hair Care Makeup Skincare Tools & Accessories
Black Cumin and Cajeput Serum Concentrate main image.
Odacité
Black Cumin and Cajeput Serum Concentrate
$36
17
Deep Acne Liquid Patch main image.
Dermalogica
Deep Acne Liquid Patch
$35
1
Blemish Balm with Plant Based Salicylic Acid main image.
OSEA
Blemish Balm with Plant Based Salicylic Acid
$54
543
Cleanance Concentrate Blemish Control Serum main image.
Avène
Cleanance Concentrate Blemish Control Serum
$36
3,851
Blemish + Age Defense main image.
SkinCeuticals
Blemish + Age Defense
$115
BestSeller
739
Breakout Box Acne Treatment Kit main image.
Patchology
Breakout Box Acne Treatment Kit
$20
501
Silymarin CF main image.
SkinCeuticals
Silymarin CF
$185
BestSeller
257
Targeted Blemish Treatment main image.
Ogee
Targeted Blemish Treatment
$38
157
PowerSpot Pad main image.
M-61
PowerSpot Pad
$34
BestSeller Exclusive
69
PowerSpot Blemish Lotion main image.
M-61
PowerSpot Blemish Lotion
$11.2
BestSeller Exclusive
51
Cleanance Acne Medicated Clearing Treatment main image.
Avène
Cleanance Acne Medicated Clearing Treatment
$32
38
Clarifying Serum main image.
Dr. Barbara Sturm
Clarifying Serum
$260
31
LightStim for Acne main image.
LightStim
LightStim for Acne
$169
7
Age Intervention Duality main image.
Jan Marini
Age Intervention Duality
$115
2
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46 main image.
EltaMD
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46
$46
BestSeller
2,294
Clearly Corrective Dark Spot Solution main image.
Kiehl's Since 1851
Clearly Corrective Dark Spot Solution
$65
1,668
Retexturing Activator main image.
SkinCeuticals
Retexturing Activator
$94
BestSeller
309
Retinol 0.5 main image.
SkinCeuticals
Retinol 0.5
$90
BestSeller
261
Acne Solutions Acne + Line Correcting Serum main image.
Clinique
Acne Solutions Acne + Line Correcting Serum
$28.5
211
TheraFace Mask main image.
Therabody
TheraFace Mask
$649.99
170
Retinol 0.3 main image.
SkinCeuticals
Retinol 0.3
$80
BestSeller
150
Perfect Peel main image.
M-61
Perfect Peel
$50.4
BestSeller Exclusive
106
Epidermal Repair main image.
SkinCeuticals
Epidermal Repair
$90
104
Active Serum main image.
IS Clinical
Active Serum
$148
BestSeller
35

When a pesky blemish tries to steal the spotlight, the best acne spot treatments are your secret weapon for a clearer, more confident complexion. Think of these targeted solutions as your personal beauty troubleshooters—ready to step in and help you face the day with poise. Whether you’re prepping for a big event or simply want to keep your skin looking its best, our curated selection empowers you to tackle breakouts head-on, so you can get back to glowing.

Best Sellers

Facial Spray With Aloe, Chamomile and Lavender 8 oz main image.
Mario Badescu
Facial Spray With Aloe, Chamomile and Lavender 8 oz
$3.5
17,575
Dramatically Different Moisturizing Lotion 4.2 oz main image.
Clinique
Dramatically Different Moisturizing Lotion 4.2 oz
$34
9,822
Crème de La Mer Face Cream 2 oz main image.
La Mer
Crème de La Mer Face Cream 2 oz
$390
8,174
Ultra Facial Cream 4.2 oz main image.
Kiehl's Since 1851
Ultra Facial Cream 4.2 oz
$70
7,960