Best Acne Spot Treatments

Bath & Body Fragrance Hair Care Makeup Skincare Tools & Accessories
Black Cumin and Cajeput Serum Concentrate main image.
Odacité
Black Cumin and Cajeput Serum Concentrate
$36
17
Truly Targeted Acne-Clearing Solution main image.
Kiehl's Since 1851
Truly Targeted Acne-Clearing Solution
$30
4,456
Blemish Balm with Plant Based Salicylic Acid main image.
OSEA
Blemish Balm with Plant Based Salicylic Acid
$54
BestSeller
Cleanance Concentrate Blemish Control Serum main image.
Avène
Cleanance Concentrate Blemish Control Serum
$40
3,852
Breakout Box Acne Treatment Kit main image.
Patchology
Breakout Box Acne Treatment Kit
$20
BestSeller
501
Targeted Blemish Treatment main image.
Ogee
Targeted Blemish Treatment
$38
164
Acne Gel With OmniSome main image.
PCA Skin
Acne Gel With OmniSome
$70
101
PowerSpot Pad main image.
M-61
PowerSpot Pad
$68
BestSeller Exclusive
69
PowerSpot Blemish Lotion main image.
M-61
PowerSpot Blemish Lotion
$16
Exclusive
51
3 Phase Anti-Blemish Booster Serum main image.
111SKIN
3 Phase Anti-Blemish Booster Serum
$67.5
50
Clarifying Serum main image.
Dr. Barbara Sturm
Clarifying Serum
$260
31
Expertly Clear Acne-Treating & Preventing Lotion main image.
Kiehl's Since 1851
Expertly Clear Acne-Treating & Preventing Lotion
$39
1,942
Clearly Corrective Dark Spot Solution main image.
Kiehl's Since 1851
Clearly Corrective Dark Spot Solution
$65
1,682
Acne Solutions Clarifying Lotion main image.
Clinique
Acne Solutions Clarifying Lotion
$22
916
Clearing Skin Wash main image.
Dermalogica
Clearing Skin Wash
$72
517
Retinol 0.3 main image.
SkinCeuticals
Retinol 0.3
$80
BestSeller
152
Epidermal Repair main image.
SkinCeuticals
Epidermal Repair
$90
108
Perfect Peel main image.
M-61
Perfect Peel
$72
BestSeller Exclusive
106
Blemish Control Bar main image.
PCA Skin
Blemish Control Bar
$62
53
Active Serum main image.
IS Clinical
Active Serum
$148
BestSeller
35
Vitablast C Dark Spot Corrector Stick main image.
M-61
Vitablast C Dark Spot Corrector Stick
$92
BestSeller Exclusive
31
Deeply Purifying Mask With Tropical Resins main image.
Sisley-Paris
Deeply Purifying Mask With Tropical Resins
$160
14
Absolute Purtiy Toner main image.
Tracie Martyn
Absolute Purtiy Toner
$65
2

When a pesky blemish tries to steal the spotlight, the best acne spot treatments are your secret weapon for a clearer, more confident complexion. Think of these targeted solutions as your personal beauty troubleshooters—ready to step in and help you face the day with poise. Whether you’re prepping for a big event or simply want to keep your skin looking its best, our curated selection empowers you to tackle breakouts head-on, so you can get back to glowing.

Best Sellers

Dramatically Different Moisturizing Lotion 4.2 oz main image.
Clinique
Dramatically Different Moisturizing Lotion 4.2 oz
$34
9,873
Crème de La Mer Face Cream 2 oz main image.
La Mer
Crème de La Mer Face Cream 2 oz
$390
8,185
Ultra Facial Cream 4.2 oz main image.
Kiehl's Since 1851
Ultra Facial Cream 4.2 oz
$72
8,028
Liquid Facial Soap OILY main image.
Clinique
Liquid Facial Soap OILY
$14
7,621