Best Acne Spot Treatments

Bath & Body Fragrance Hair Care Makeup Skincare Tools & Accessories
PowerSpot Blemish Lotion main image.
M-61
PowerSpot Blemish Lotion
$16
Exclusive
51
Black Cumin and Cajeput Serum Concentrate main image.
Odacité
Black Cumin and Cajeput Serum Concentrate
$36
17
Blemish Balm with Plant Based Salicylic Acid main image.
OSEA
Blemish Balm with Plant Based Salicylic Acid
$54
BestSeller
Silymarin CF main image.
SkinCeuticals
Silymarin CF
$185
BestSeller
261
Blackhead Solutions Self-Heating Blackhead Extractor main image.
Clinique
Blackhead Solutions Self-Heating Blackhead Extractor
$36
123
Acne Gel With OmniSome main image.
PCA Skin
Acne Gel With OmniSome
$72
101
3 Phase Anti-Blemish Booster Serum main image.
111SKIN
3 Phase Anti-Blemish Booster Serum
$67.5
50
Clarifying Serum main image.
Dr. Barbara Sturm
Clarifying Serum
$260
31
PowerSpot Clear main image.
M-61
PowerSpot Clear
$12.6
Exclusive
21
LightStim for Acne main image.
LightStim
LightStim for Acne
$169
7
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46 main image.
EltaMD
UV Clear Tinted Broad-Spectrum Facial Sunscreen SPF 46
$46
BestSeller
3,028
Expertly Clear Acne-Treating & Preventing Lotion main image.
Kiehl's Since 1851
Expertly Clear Acne-Treating & Preventing Lotion
$39
1,942
Acne Solutions Clarifying Lotion main image.
Clinique
Acne Solutions Clarifying Lotion
$22
916
Retexturing Activator main image.
SkinCeuticals
Retexturing Activator
$94
BestSeller
316
TheraFace Mask main image.
Therabody
TheraFace Mask
$649.99
BestSeller
171
Retinol 0.3 main image.
SkinCeuticals
Retinol 0.3
$80
BestSeller
153
Epidermal Repair main image.
SkinCeuticals
Epidermal Repair
$90
109
Perfect Peel main image.
M-61
Perfect Peel
$72
BestSeller Exclusive
106
Blemish Control Bar main image.
PCA Skin
Blemish Control Bar
$62
53
Active Serum main image.
IS Clinical
Active Serum
$148
BestSeller
35
Phyto-Blanc Targeted Dark Spot Corrector main image.
Sisley Paris
Phyto-Blanc Targeted Dark Spot Corrector
$215
8
Absolute Purtiy Toner main image.
Tracie Martyn
Absolute Purtiy Toner
$65
2
Clenziderm M.D. Pore Therapy main image.
Obagi
Clenziderm M.D. Pore Therapy
$49
1

When a pesky blemish tries to steal the spotlight, the best acne spot treatments are your secret weapon for a clearer, more confident complexion. Think of these targeted solutions as your personal beauty troubleshooters—ready to step in and help you face the day with poise. Whether you’re prepping for a big event or simply want to keep your skin looking its best, our curated selection empowers you to tackle breakouts head-on, so you can get back to glowing.

Best Sellers

Dramatically Different Moisturizing Lotion 4.2 oz main image.
Clinique
Dramatically Different Moisturizing Lotion 4.2 oz
$34
9,878
Crème de La Mer Face Cream 2 oz main image.
La Mer
Crème de La Mer Face Cream 2 oz
$390
8,189
Ultra Facial Cream 4.2 oz main image.
Kiehl's Since 1851
Ultra Facial Cream 4.2 oz
$72
8,050
Liquid Facial Soap MILD main image.
Clinique
Liquid Facial Soap MILD
$28
7,623